>(For instance, huge Transformers geek, never played Mass Effect.)

You should, if you like RPGs and don't absolutely loathe first-person shooters. I didn't try ME until a year or two ago, because of the FPS aspects, but I finally got interested enough to try it thanks to Gryphon et al (I believe it was Star-crossed that did it, but I may be mixing up the order of events) and really liked it.