I can't help but think of GlaDOS as being in the exact same position as Cortana now--Chell's AI aide--but well past 'viciously sarcastic' and into 'casually homicidal'. Who knows what sitting around on that Covenant ship (in stasis?) has done to them?

Either way, I'm very much looking forward to finding out.

"They say one should not speak unkindly of the dead, so I say, 'nice try'." --Lezard