[ EPU Foyer ] [ Lab and Grill ] [ Bonus Theater!! ] [ Rhetorical Questions ] [ CSRANTronix ] [ GNDN ] [ Subterranean Vault ] [ Discussion Forum ] [ Gun of the Week ]

Eyrie Productions, Unlimited

Subject: "Study suggests EBV-MS link"     Previous Topic | Next Topic
Printer-friendly copy    
Conferences General Topic #1716
Reading Topic #1716
Gryphonadmin
Charter Member
21386 posts
Jan-15-22, 00:44 AM (EST)
Click to EMail Gryphon Click to send private message to Gryphon Click to view user profileClick to add this user to your buddy list  
"Study suggests EBV-MS link"
 
   A newly published paper in the venerable journal Science suggests a link between Epstein-Barr virus, the incredibly common virus that causes mononucleosis, and multiple sclerosis. The same issue of Science also contains an editorial article seeking to explicate the paper to non-biochemists.

The super-short version is that researchers dug through the medical records of 10 million United States armed services personnel going back ~20 years, and discovered evidence suggesting that people who have been infected with EBV are 32 times more likely to develop MS thereafter, "comparable to the increase in risk of getting lung cancer from heavy smoking."

Technically speaking, what the authors of the study are asserting is not that EBV causes MS, although it's a tempting shorthand. It looks to me like what they believe is that the immune malfunction's origin is genetic, but EBV infection triggers MS in people who are genetically predisposed to it.

Meanwhile, it so happens that Moderna, one of the companies making a COVID-19 vaccine, has been trying the same developmental approach on a vaccine for EBV, which is just now entering early trials. That does those of us who already have MS fuck-all good in itself, of course, but if this line of inquiry is borne out by follow-up research, a better understanding of the condition's underlying mechanisms may emerge, which opens the possibility that someone might someday figure out how to turn it off. Reversing the damage already done is still probably too much to hope for, but heading off further degeneration would be something, all the same.

I'll be honest, I'm not as excited by this result for my own sake as I would have been 10 years ago, because I can plot the typical pace of medical science's advance vs. my own actuarial possibilities, and I don't like where I see those two curves most likely crossing. But who knows? I didn't think monoclonal antibodies would amount to anything within my lifetime either, and the damn things are everywhere now.

--G.
-><-
Benjamin D. Hutchins, Co-Founder, Editor-in-Chief, & Forum Mod
Eyrie Productions, Unlimited http://www.eyrie-productions.com/
zgryphon at that email service Google has
Ceterum censeo Carthaginem esse delendam.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
The Traitor
Member since Feb-24-09
1099 posts
Jan-16-22, 10:00 AM (EST)
Click to EMail The%20Traitor Click to send private message to The%20Traitor Click to view user profileClick to add this user to your buddy list  
1. "RE: Study suggests EBV-MS link"
In response to message #0
 
   This is an incredible development, and I really hope it pans out with something interesting for EBV-related conditions as well as MS. Part of me is now wondering if there's a connection between this and stuff like fibromyalgia and myalgic encephalopathy, given the research currently underway with regards to "long Covid" and post-viral fatigue syndrome.

---
"She's old, she's lame, she's barren too, // "She's not worth feed or hay, // "But I'll give her this," - he blew smoke at me - // "She was something in her day." -- Garnet Rogers, Small Victory

FiMFiction.net: we might accept blatant porn involving the cast of My Little Pony but as God is my witness we have standards.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
MuninsFire
Member since Mar-27-07
446 posts
Jan-16-22, 10:34 PM (EST)
Click to EMail MuninsFire Click to send private message to MuninsFire Click to view user profileClick to add this user to your buddy list  
2. "RE: Study suggests EBV-MS link"
In response to message #1
 
   My various friends with ME/CFS certainly seem to think it's a likely avenue of investigation.

Kinda wondering if certain things like parkinson's and the like are implicated too. Having some real lovecraftian-horror vibes < think The Alchemist, but with mono parties instead of a wizard > and wondering just how many "things that run in families" derive from....this.

In Xanadu did Kubla Khan
A stately pleasure-dome decree
Where Alph, the sacred river, ran
Through caverns measureless to man
Down to a sunless sea


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Verbena
Charter Member
973 posts
Jan-17-22, 08:47 AM (EST)
Click to EMail Verbena Click to send private message to Verbena Click to view user profileClick to add this user to your buddy list  
3. "RE: Study suggests EBV-MS link"
In response to message #2
 
   I find this whole avenue a fascinating one, although I do not really have much knowledge of medicine.

In a more general sense, I think it's helpful to highlight just how much we still don't know. It's good to re-examine things and keep an open mind.


------
Authors of our fates
Orchestrate our fall from grace
Poorest players on the stage
Our defiance drives us straight to the edge


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top

Conferences | Topics | Previous Topic | Next Topic

[ YUM ] [ BIG ] [ ??!? ] [ RANT ] [ GNDN ] [ STORE ] [ FORUM ] GOTW ] [ VAULT ]

version 3.3 © 2001
Eyrie Productions, Unlimited
Benjamin D. Hutchins
E P U (Colour)